錢嘉琳  教授

 

 

  聯絡方式

研究室:(03)-863-3589
實驗室:(03)-863-3590

  辦公室

 理D421

  Email

chyan@mail.ndhu.edu.tw

  Office Hour

禮拜 09:10-11:00

 

  實驗室個別網頁網址

 

  主要學歷

 
1980-1984: 國立清華大學化學系學士

1988-1994: Rutgers University化學博士
 

  現職經歷


1988-1991: Rutgers University TA

1991-1994: Rutgers University RA

1994-1999: 中央研究院生醫所博士後研究

1999-2005.08: 國立東華大學化學系助教授

2005.08-至今: 國立東華大學化學系副教授
 

  研究方向

 

1.          生物化學

2.          生物核磁共振光譜

3.          生物物理化學

4.          結構生物學

 

  學術著作

 

1.      H.-b. Huang, Y.-C. Chen, A. Horiuchi, L.-H. Tsai, H.-T. Liu, C.-L. Chyan, M.-J. Hsieh, C.-K. Liu, F.-M. Lin, P. Greengard, A. C. Nairn, M.-S. Shiao, T.-H. Lin*, “Backbone 1H, 15N, and 13C Resonance Assignments of ARPP-19” J. of Biomol. NMR 19 (4), 383-384 (2001) (SCI 4.636).

 

2.      C.-L. Chyan, T. C. Tang, Y.-c. Chen, H.-t. Liu, F.-M. Lin, C.-K. Liu, M.-J. Hsieh, M.-S. Shiao, H.-b. Huang and T.-H. Lin*, “Backbone 1H, 15N, and 13C Resonance Assignments of Inhibitor-1 – a Protein Inhibitor of Protein Phosphatase-1”, J. of Biomol. NMR 21(3), 287-288 (2001) (SCI 4.636).

 

3.      T.-H. Lin, Y.-c. Chen, C.-L. Chyan, L.-H. Tsay, T. C. Tang, H.-H. Jeng, F.-M. Lin, H.-b. Huang*, “Phosphorylation by glycogen synthase kinase of inhibitor-2 does not change its structure in free state”, FEBS Lett. 554(3), 253-6 (2003) (SCI 3.609).

 

4.      Y.-L. Yeh, C.-H. Chang, C.-L. Chyan, and S.-H. Lin, “Atomic Force Microscopic and Theoretical Study of Protein Folding and Unfolding”, Instruments Today 25 (5), 39-45 (2004)

 

5.      T.-H. Lin, J.-W.Huang, H..-b.. Huang, Y..-c.. Chen, C.-Y. Liu, C.-j. Lo, T. C. Tang, and C.-L. Chyan*, “1H, 15N, and 13C Resonance Assignments of Calmodulin Complexed with the Calmodulin-Binding Domain of Protein Phosphatase 2B”, J. of Biomol. NMR, 29, 531-2 (2004) (SCI 2.420).

 

6.      C.-M. Chen, C.-L. Chyan, T.-T. Lee, S.-H. Huang, and J. T.C. Tzen*, “Caleosin Stabilizes Artificial Oil Bodies as Nanoparticles”, J. of Agri. And Food Chem. 52 (12), 3982-7 (2004) (SCI 2.102).

 

7.      J.-H. Shyu, C.-L. Chyan, J. T. C. Tzen, and W.-M. Chou*, “Molecular Cloning, Expression, and Functional Characterization of a Cystatin from Pineapple Stem”, Bioscience, Biotechnology, and Biochemistry 68, 1681-1689 (SCI 1.025).

 

8.      C.-L. Chyan, F.-C. Lin, H. Peng, J.-M. Yuan, C.-H. Chang, S.-H. Lin, and G. Yang*, ‘Reversible Mechanical Unfolding of Single Ubiquitin Molecules”, Biophysical J. 87, 3995-4006 (SCI 4.463).

 

9.      Y.L. Yeh*, C.H. Chang, K.K. Liang , Y.J. Shiu, C. Su, M. Hayashi, C.-L. Chyan, G. Yang, Y. Moe, YJ Yan, S.H. Lin, “Atomic force microscopic and theoretical studies of poly-ubiquitin  proteins”, Chemical Physics Letters 399, 440–445 (2004) (SCI 2.438).

 

10. C.-L. Chyan*, P.-C. Huang, T.-H. Lin, J.-W. Huang, S.-S. Lin, H.-b. Huang and Y.-C. Chen*, “Purification, crystallization and preliminary crystallographic studies of the Camodulin-OLFp complex” Acta Crystallographica F61, 785-787 (2005) (SCI 1.693).

 

11. C.-L. Chyan, T.T.-T. Lee, C.-P. Liu, Y.-C. Yang, J.T.-C. Tzen, and W.-M. Chou*, “Cloning and Expression of a Seed-Specific Metallothionein-Like Protein from Sesame Bioscience, Biotechnology, and Biochemistry 69 (12), 2319-2325 (2005) (SCI 1.025).